In this series, Digital Health Business & Technology interviews a range of digital health investors from those who work at venture capital firms and at health system and health insurance venture funds to individual and angel investors. If you’re interested in participating, email us here.
Lynne Chou O’Keefe founded Define Ventures in 2018 at a time when there weren't many digital health-focused venture capital firms in Silicon Valley.
“There were firms that either dabbled in healthcare [as a generalist Silicon Valley venture capital firm] or had deep healthcare backgrounds but didn’t have Silicon Valley principals,” O’Keefe said. “That’s where Define was born.”
Define has invested in 21 startups out of three funds across Seed, Series A and Series B rounds. Some of its notable portfolio companies include direct-to-consumer telehealth company Hims, women’s health startup Tia and value-based primary care services and technology company UpStream.
O’Keefe spoke about why she was all in on hybrid healthcare models before it became trendy, her advice to entrepreneurs during “war times” and more. The interview has been edited for length and clarity.